Dr. Rositsa Ivanova and colleagues in Dr. Guy Moss’s group in University of College London recently published a new paper on ACS Applied Materials and Interfaces, which is about using nanopipette on SICM as a toolbox to measure the airway surface liquid (ASL) and epithelial cell function in many different ways that were only possible with a range of instruments. By utilising the precise positioning and ion current feedback in SICM, they managed to measure trans-epithelial potential, ASL depth, Cilia beat frequency, ASL pH and spinnability, all on a single platform SICM (Ionscope) without any need for labelling. With such an approach, the studies on major diseases where ASL and/or mucociliary transport are affected can be accelerated, become more coherent and more informative.

Please check this link to read the paper https://pubs.acs.org/doi/10.1021/acsami.8b14122

The post SICM as a toolbox for airway surface liquid measurement appeared first on Ionscope.

About the Author

I'm Kirsty, and Marketing Specialist at Synoptics covering the Syngene, Synbiosis, Gallenkamp and Fistreem brands. I have been working at Synoptics since the start of 2023 and come from a B2B agency and in-house. I also have experience working at Anglian Waters Central Laboratory in this industry.

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